mucociliary clearance | Rare Diseases Clinical Research Network

New Lung Disease Reveals Gene Regulating Airway Mucociliary Clearance Dakota Campbell Tue, 05/05/2020 - 15:54

What is the genetic cause behind impaired mucociliary clearance of the lungs? Researchers from the Genetic Disorders of Mucociliary Clearance Consortium (GDMCC) contributed to the discovery of a new disease gene, NEK10, that regulates cilia length.

Genetic Disorders of Mucociliary Clearance Consortium

GDMCC

mucociliary clearance

bronchiectasis

cystic fibrosis

CF

primary ciliary dyskinesia

PCD

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The Rare Diseases Clinical Research Network (RDCRN) is funded by the National Institutes of Health (NIH) and led by the National Center for Advancing Translational Sciences (NCATS) through its Office of Rare Diseases Research (ORDR). The RDCRN websites are hosted by the network’s Data Management and Coordinating Center at Cincinnati Children’s Hospital Medical Center, which is funded by NCATS and the National Institute of Neurological Disorders and Stroke (NINDS) under grant number TR002818.